7-Chloro-2-phenyl-quinoline is an organic compound with the chemical formula C16H10ClN. It is a yellow solid with a special structure of chlorobenzene and quinoline. The following is a description of the properties, uses, preparation and safety information of 7-Chloro-2-phenyl-quinoline:
Nature:
-Appearance: Yellow solid
-melting point: about 135-140 ℃
-Solubility: It can be dissolved in some organic solvents, such as dimethyl sulfoxide and dimethylformamide, but the solubility in water is low.
Use:
- 7-Chloro-2-phenyl-quinoline can be used as an intermediate in organic synthesis. It can be used to synthesize compounds with fluorescent properties, such as fluorescent dyes and fluorescent probes.
-In addition, 7-Chloro-2-phenyl-quinoline can also be used to prepare compounds such as medicines and pesticides.
Preparation Method:
- 7-Chloro-2-phenyl-quinoline can be prepared by chlorination of p-phenylquinoline under the catalysis of hydrogen bromide acid. The reaction conditions are generally under acidic conditions at room temperature or with heating for a period of time.
Safety Information:
- 7-Chloro-2-phenyl-quinoline is relatively stable under general conditions, but contact with oxidants, acidic substances and strong oxidants should be avoided.
-Wear appropriate personal protective equipment, such as gloves and glasses, when used or handled to avoid contact with eyes, skin or respiratory tract.
-During storage and handling, care should be taken to avoid fire and high temperatures.